Useful Texbooks

Atkinson, A., Abernathy, D., Daniels, C., Dedrick, R., & Markey, S. (2007). Principles of Clinical Pharmacology (2nd ed.): Academic Press.
Bonate, P. (2011). Pharmacokinetic-Pharmacodynamic Modeling and Simulation (2nd ed.): Springer
Burton, M., Shaw, L., Schentag, J. J., & Evans, W. (2006). Applied Pharmacokinetics and Pharmacodynamics (Vol. 4th): Lippincott Williams & WIlkins.
Ette, E. I., & Williams, P. (2007). Pharmacometrics. The Science of Quantitative Pharmacology (1st ed.). Hoboken: Wiley.
Gibaldi, M., & Perrier, D. (2007). Pharmacokinetics (2nd ed.). New York: Informa Healthcare.
Rosenbaum, SE. (2011). Basic Pharmacokinetics and Pharmacodynamics.An Integrated Textbook and Computer Simulations (1st ed.). Hoboken: Wiley.
Rowland, M., & Tozer, T. (2011). Clinical Pharmacokinetics and Pharmacodynamics. Concepts and Applications (4th ed.). Baltimore: Lippincott Williams & Wilkins.
Shargel, L., Wu-Pong, S., & Yu, A. B. C. (2004). Applied Biopharmaceutics and Pharmacokinetics (5th ed.). New York: McGraw-Hill.
Tozer, T., & MR, R. (2006). Intorduction to Pharmacokinetics and Pharmacodynamics. The Quantitative Basis of Drug Therapy (1st Edition ed.): Lippincott Williams & Wilkins.
Wagner, J. (1993). Pharmacokinetics For the Pharmaceutical Scientist: Technomic.


Useful Literature

Danhof, M., de Jongh, J., De Lange, E. C., Della Pasqua, O., Ploeger, B. A., & Voskuyl, R. A. (2007). Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis. Annu Rev Pharmacol Toxicol, 47, 357-400.
Dayneka, N. L., Garg, V., & Jusko, W. J. (1993). Comparison of four basic models of indirect pharmacodynamic responses. J Pharmacokinet Biopharm, 21(4), 457-478.
Holford, N., & Karlsson, M. O. (2007). Time for quantitative clinical pharmacology: a proposal for a pharmacometrics curriculum. Clin Pharmacol Ther, 82(1), 103-105.
Holford, N. H., & Sheiner, L. B. (1981). Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models. Clin Pharmacokinet, 6(6), 429-453.
Jusko, W. J., & Ko, H. C. (1994). Physiologic indirect response models characterize diverse types of pharmacodynamic effects. Clin Pharmacol Ther, 56(4), 406-419.
Mager, D. E., Wyska, E., & Jusko, W. J. (2003). Diversity of mechanism-based pharmacodynamic models. Drug Metab Dispos, 31(5), 510-518.
Peck, C. C., Barr, W. H., Benet, L. Z., Collins, J., Desjardins, R. E., Furst, D. E., et al. (1994). Opportunities for integration of pharmacokinetics, pharmacodynamics, and toxicokinetics in rational drug development. J Clin Pharmacol, 34(2), 111-119.
Ploeger, B. A., van der Graaf, P. H., & Danhof, M. (2009). Incorporating receptor theory in mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling. Drug Metab Pharmacokinet, 24(1), 3-15.
Sharma, A., & Jusko, W. J. (1998). Characteristics of indirect pharmacodynamic models and applications to clinical drug responses. Br J Clin Pharmacol, 45(3), 229-239.
Sheiner, L. B., & Ludden, T. M. (1992). Population pharmacokinetics/dynamics. Annu Rev Pharmacol Toxicol, 32, 185-209.
Wagner, J. A. (2009). Biomarkers: principles, policies, and practice. Clin Pharmacol Ther, 86(1), 3-7.